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Nursing Science Quarterly
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The Theory of Genetic Vulnerability: A Roy Model Exemplar

Rebekah J. Hamilton, RN; PhD

University of Pittsburgh, Pittsburgh, Pennsylvania,

Barbara J. Bowers, RN; PhD; FAAN

Dean of Research, University of Wisconsin-Madison, Madison, Wisconsin

The purpose of this study was to explore the experience of adult genetic testing. Grounded theory was used to plan, guide, and analyze in-depth interviews with 29 participants. The theory of genetic vulnerability was developed and is composed of five concepts: (a) experiencing the family disease, (b) testing for a mutation, (c) fore-grounding inherited disease risk, (d) responding to knowledge of genetic vulnerability, and (e) altering or avoiding the family experience of inherited disease. Roy's model of adaptation is discussed as a valuable lens through which to test and adapt this theory.

Key Words: genetic risk • grounded theory • Roy's adaptation model

Nursing Science Quarterly, Vol. 20, No. 3, 254-264 (2007)
DOI: 10.1177/0894318407303127
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